Archive 1992–2014
1997, tom 6, zeszyt 1
Varia
Current views on the pathogenesis of paraneoplastic syndromes, wit h t he focus on the role of antineuronal antibodies – diagnostic and therapeutic implications
JERZY SŁOWIŃSKI1
1. Katedry i Kliniki Neurochirurgii i Neurotraumatologii Śląskiej AM w Bytomiu
Postępy Psychiatrii i Neurologii, 1997, 6, 79-87
Keywords: paraneoplastic syndrome, antineuronal antibodies
Summary
Views on the pathogenesis of neurological paraneoplastic syndromes are presented, focusing on the role of antineuronal antibodies. A current classification of these antibodies is discussed, as well as methods of their identification in the serum and cerebrospinal fluid. Mechanisms probably involved in the damaging on the CNS in the course of paraneoplastic syndromes are described. Particular attention was paid to the practical aspects of knowledge on antineuronal antibodies, pertaining, above all, to the early diagnosis of the paraneoplastic syndrome and possibilities of its treatment.
Correspondence address
Dr Jerzy Słowiński,
ul. Łapkowskiego 20/7,
41-813 Zabrze
ul. Łapkowskiego 20/7,
41-813 Zabrze