Advances in psychiatry and nuerology


ISSN 1230-2813
ISSN online 2720-5371 

JCR Impact Factor: 1.5
CiteScore 2025: 2.0
MNiSW: 70
Index Copernicus 2023: 153.00

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  • The role of the tumor necrosis factor alpha (TNF-alpha) in the pathogenesis of multiple sclerosis

Archive 1992–2014

1997, tom 6, zeszyt 1
Varia

The role of the tumor necrosis factor alpha (TNF-alpha) in the pathogenesis of multiple sclerosis

ANITA GEPPERT1, Jacek Losy1
1. Katedry i Kliniki Neurologii AM w Poznaniu
Postępy Psychiatrii i Neurologii, 1997, 6, 73-77
Keywords: TNF-alpha, multiple sclerosis
Summary

Numerous data suggest that cytokines play an important role in the multiple sclerosis pathophysiology, both through regulation of inappropriate immunological reactions and through mediation in myelin damage. The TNF-alpha, as one of the main mediators of the inflammatory reaction, plays and important role in the pathogenesis of multiple sclerosis. The role of TNF-alpha in the multiple sclerosis is discussed in the paper.

Correspondence address
Dr Anita Geppert,
Katedra i Klinika Neurologii AM,
ul. Przybyszewskiego 49,
60-355 Poznań
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